ORAL ADMINISTRATION OF P-HYDROXYCINNAMIC ACID ATTENUATES ATOPIC DERMATITIS BY DOWNREGULATING TH1 AND TH2 CYTOKINE PRODUCTION AND KERATINOCYTE ACTIVATION.

Atopic dermatitis (AD) is a complex disease that is caused by various factors, including environmental change, genetic defects, and immune imbalance.We previously showed that p-hydroxycinnamic acid (HCA) isolated from the Extra Heavy Duty roots of Curcuma longa inhibits T-cell activation without inducing cell death.Here, we demonstrated that oral a

BackgroundNotch signaling is an evolutionarily conserved regulatory circuitry implicated in cell fate determination in various developmental processes including hematopoietic stem cell self-renewal and differentiation of blood lineages.Known endogenous inhibitors of Notch activity are Numb-Nb and Numblike-Nbl, which play partially redundant functio

ABSTRACT Background: Adolescence is a transitional period between the time of children with adulthood.There are still many found little regard for teens on health on reproductive, will consequently risk against the occurrence of an increase in diseases, among others; Sexually Transmitted Infections (STI).Methods: This type of research is the pre-de

In this paper, the preliminary results of computational modeling of an aircraft with the airbrake deployed are presented.The tumbler calculations were performed with OpenFOAM software package.The results outlined are a part of a research project to optimise aircraft performance using a perforated airbrake.Within this stage of the project OpenFOAM s

Objective To evaluate the clinical usefulness of the Korean Developmental Screening Test (K-DST) via comparison with Korean Ages and Stages Questionnaire (K-ASQ) for the diagnosis of developmental delay in pediatric patients.Methods The K-DST and K-ASQ were used to screen pediatric patients who visited the hospital for evaluation and diagnosis of d